Could be a couple of things:
- The file is marked as read-only. Right click on file, uncheck “read only”.2. The application pool identity doesn’t have write permissions to the folder that contains the MDB. Find the identity of the application pool (using IIS) and (using Windows Explorer) give that identity (usually Network Service) write permissions to the folder.'3. Check this KB for more possible reasons: http://support.microsoft.com/kb/175168
Jon Gallant
dev lead @ microsoft